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Though its appearance is not appealing, Xylaria nigripes (Klotzsch) Cooke, also called O Linh ginseng, is a highly valued medicinal fungus. In traditional medicine, it is used for its sedative effects, to treat insomnia, stop bleeding, lower blood pressure, improve memory, and nourish both the brain and kidneys. It is especially recommended for people recovering from surgery, childbirth, or during breastfeeding due to its restorative properties.
According to ncbi.nlm.nih.gov, Xylaria nigripes (XN), from the family Xylariaceae, has long been applied as a remedy for trauma and as a nerve tonic. Modern research confirms its multiple bioactivities, including antioxidant, anti-inflammatory, immunomodulatory, hepatoprotective, neuroprotective, and anti-depressant effects. Studies also highlight its role in enhancing insulin sensitivity and preventing spatial memory impairment.
These health benefits are linked to its rich chemical composition, including polysaccharides, adenosine, polyphenols, and triterpenoids. Experimental models show XN extracts protect neural cells from oxidative stress induced by hydrogen peroxide (H2O2).
